San Francisco Giants vs. Cleveland Guardians MLB Betting Tips and Best Bets

by | Apr 14, 2022

The Cleveland Guardians (4-2) and Myles Straw, coming off a four-hit game, are underdogs (+145) on the moneyline and will look to upset the San Francisco Giants (4-2) on Friday at 7:10 PM ET. Carlos Rodon will get the ball for San Francisco while Cleveland counter with Zach Plesac.

San Francisco Giants vs. Cleveland Guardians: Predictions, Betting Odds, Spread, Line

Giants vs Guardians Betting Information
Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Spread Favorite Spread Odds Underdog Spread Odds
Giants -165 +145 8.5 -110 -110 -1.5 -105 -115

Computer Predictions for Giants vs. Guardians

Our computer pick: Cleveland Guardians (+145) and Over (8.5)

Giants vs. Guardians Game Info

  • San Francisco Giants probable starting pitcher: Carlos Rodón
  • Cleveland Guardians probable starting pitcher: Zach Plesac
  • Game Day: Friday, April 15, 2022
  • Game Time: 7:10 PM ET
  • Location: Cleveland, Ohio
  • Stadium: Progressive Field

San Francisco Giants vs Cleveland Guardians Pitching Matchup

Rodón Plesac
1 GS 1
0-0 W-L 0-0
1.80 ERA 0.00
5.0 IP 5.2
2 BB 0
12 SO 3

Giants Starter Carlos Rodón

  • Rodon (0-0) starts for the Giants, his second this season.
  • His most recent time out came on Saturday against the Miami Marlins, when the left-hander went 5 2/3 innings, surrendering one earned run while giving up three hits.
  • Opposing hitters have a collective batting average of only .167 against him this season. He has a 1.80 ERA and 21.6 strikeouts per nine innings over his one appearances.
  • He meets a Guardians offense that ranks first in the league with 45 runs while batting .308 as a unit. It has a collective .524 slugging percentage (second in MLB action) and has hit a total of nine home runs (second in MLB).

Guardians Starter Zach Plesac

  • Plesac will get the start for the Guardians, his second of the season.
  • The right-hander’s last appearance was on Saturday, when he threw 5 2/3 scoreless innings while allowing three hits against the Kansas City Royals.
  • He has pitched to a .00 ERA this season with 4.8 strikeouts per nine innings compared to 0 walks per nine across one games.
  • The Giants rank sixth in MLB with 27 runs scored this season. They have a .241 batting average this campaign with six home runs (11th in the league).

Giants Betting Picks & Insights

  • Last season, the Giants won 70 out of the 98 games, or 71.4%, in which they were favored.
  • San Francisco entered 47 games last season favored by -165 or more and was 35-12 in those contests.
  • The implied probability of a win by the Giants, based on the moneyline, is 62.3%.
  • San Francisco’s games went over the total in 74 of their 164 chances last season.
  • The Giants were 74-46-0 against the spread in their 120 chances last season.

Guardians Betting Picks & Insights

  • The Guardians won in 38, or 41.8%, of the 91 contests they were named as odds-on underdogs in last year.
  • Last season, Cleveland was victorious 10 times in 29 chances when named as an underdog of +145 or worse on the moneyline.
  • The moneyline set for this matchup implies the Guardians have a 40.8% chance of coming away with a victory in the contest.
  • Cleveland and its opponents went over the total last season in 82 of their 157 opportunities.
  • The Guardians went 58-53-0 against the spread in their 111 games with a line set by sportsbooks last season.

Giants Leaders & Batting Stats

  • Brandon Crawford put up a batting average of .298 with 90 runs batted in last season.
  • Mike Yastrzemski had 28 doubles, three triples, 25 home runs and 51 walks while hitting .224.
  • Wilmer Flores hit .262 a season ago with 16 doubles, a triple, 18 home runs and 41 walks.
  • Brandon Belt hit 29 home runs on the season while slugging .597.
Name GP BA OBP SLG HR RBI H
Brandon Belt 4 .438 .526 .875 2 3 7
Thairo Estrada 6 .238 .273 .429 1 4 5
Wilmer Flores 5 .278 .300 .500 1 3 5
Joey Bart 5 .286 .444 .571 1 2 4
Darin Ruf 6 .238 .407 .333 0 1 5

Guardians Leaders & Batting Stats

  • Jose Ramirez put up 36 home runs and had 103 runs batted in last season.
  • Straw hit .271 with 29 doubles, a triple, four home runs and 67 walks.
  • Amed Rosario had a batting average of .282 with 155 total hits last season.
  • Franmil Reyes had 18 doubles, two triples, 30 home runs and 43 walks while hitting .254.
Name GP BA OBP SLG HR RBI H
José Ramírez 6 .480 .536 1.040 3 14 12
Owen Miller 6 .524 .545 1.048 2 6 11
Steven Kwan 6 .526 .655 .737 0 5 10
Myles Straw 6 .360 .484 .400 0 0 9
Oscar Mercado 6 .200 .200 .680 3 9 5

Betting Tips for Giants vs. Guardians

We have the Guardians on the moneyline at +145 on the moneyline as our best bet in this contest after taking a look at all of the key trends and stats for this matchup. Our computer prediction sees the scoring going over the total of 8.5 runs.

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