Cubs vs. Pirates Prediction, Betting Tips & Picks 4/21/2022

by | Apr 21, 2022

A losing streak will come to an end Thursday when the Chicago Cubs (6-6), losers of two straight, take on the Pittsburgh Pirates (5-7). The Pirates are hoping to avoid their third loss in a row. The Cubs are -142 favorites to snap out of their slide when the teams hit the field at Wrigley Field, with first pitch at 7:40 PM ET. Mark Leiter Jr. gets the starting nod for Chicago while Bryse Wilson is Pittsburgh’s starter for the contest.

Cubs vs. Pirates Spread and Betting Line

Cubs vs Pirates Betting Information
Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Spread Favorite Spread Odds Underdog Spread Odds
Cubs -142 +121

Computer Predictions for Cubs vs. Pirates

Our computer pick: Pittsburgh Pirates (+121)

Cubs vs. Pirates Game Info

  • Chicago Cubs probable starting pitcher: Mark Leiter Jr.
  • Pittsburgh Pirates probable starting pitcher: Bryse Wilson
  • Game Day: Thursday, April 21, 2022
  • Game Time: 7:40 PM ET
  • Location: Chicago, Illinois
  • Stadium: Wrigley Field

Chicago Cubs vs Pittsburgh Pirates Pitching Matchup

Leiter Jr. Wilson
1 GS 2
0-1 W-L 0-0
18.90 ERA 5.40
3.1 IP 8.1
4 BB 4
4 SO 4

Cubs Starter Mark Leiter Jr.

  • Mark Leiter Jr. (0-1) takes the mound for the Cubs to make his second start of the season.
  • The righty last pitched on Sunday against the Colorado Rockies, when he tossed 3 1/3 innings, allowing seven earned runs while giving up five hits.
  • In one games this season, he has compiled an 18.90 ERA and averages 10.8 strikeouts per nine innings while opposing batters are hitting .357 against him.
  • He meets a Pirates offense that ranks 16th in the league with 45 runs while batting .244 as a squad. It has a collective .354 slugging percentage (17th in MLB play) and has hit a total of eight home runs (23rd in MLB).

Pirates Starter Bryse Wilson

  • The Pirates will send Wilson to the mound for his third start of the season.
  • The right-hander’s last appearance was on Saturday, when he threw 4 1/3 innings, giving up two earned runs while allowing four hits against the Washington Nationals.
  • He has an ERA of 5.40, a batting average against of .281 and 4.3 strikeouts per nine innings in two games this season.
  • The Cubs have scored 55 runs this season, which ranks seventh in MLB. They are batting .263 for the campaign with 11 home runs, 10th in the league.

Cubs Betting Picks & Insights

  • The Cubs have split the two games they’ve played as favorites this season.
  • Chicago has not entered a game this season as a bigger favorite on the moneyline than the -142 odds on them winning this game.
  • Sportsbooks have implied with the moneyline set for this matchup that the Cubs have a 58.7% chance to win.
  • Chicago and its opponents have hit the over in six of their 12 games with a total this season.
  • The Cubs are 8-4-0 ATS in their 12 games with a spread this season.

Pirates Betting Picks & Insights

  • The Pirates have been chosen as underdogs in nine games this year and have walked away with the win three times (33.3%) in those games.
  • Pittsburgh has a win-loss record of 1-5 when favored by +121 or worse by oddsmakers this year.
  • The Pirates have an implied victory probability of 45.2% according to the moneyline set by sportsbooks for this matchup.
  • Pittsburgh and their opponents have gone over in four of their 12 games with a total set by sportsbooks this season.
  • In 12 games with a line this season, the Pirates have a mark of 6-6-0 against the spread.

Cubs Leaders & Batting Stats

  • Seiya Suzuki’s four homers and 11 RBI both lead the Cubs, in addition to his team-high .387 average.
  • Suzuki’s home runs place him fifth in MLB, and he is fifth in RBI.
  • Suzuki carries a five-game hitting streak into this matchup. During his last five outings he is batting .417 with a double, a home run, seven walks and an RBI.
  • Frank Schwindel is batting .261 with three doubles, two home runs and two walks.
  • Of all major league hitters, Schwindel is 29th in home runs and 36th in RBI.
  • Schwindel enters this game looking for his third game in a row with a hit. During his last five outings he is batting .250 with three doubles, a home run and four RBI.
  • Patrick Wisdom is hitting .250 with five doubles, two home runs and three walks.
  • Willson Contreras has three doubles, two home runs and three walks while hitting .229.
  • Contreras takes a three-game streak with at least one hit into this one. During his last five outings he is hitting .182 with two doubles, a home run, a walk and two RBI.
Seiya Suzuki 12 .387 .565 .839 4 11 12
Frank Schwindel 12 .261 .292 .457 2 7 12
Patrick Wisdom 11 .250 .300 .556 2 10 9
Willson Contreras 9 .229 .325 .486 2 3 8
Ian Happ 11 .333 .400 .389 0 6 12

Pirates Leaders & Batting Stats

  • Michael Chavis has driven in a team-leading six runs batted in.
  • In all of MLB, Chavis ranks 78th in home runs and 56th in RBI.
  • Daniel Vogelbach’s two home runs are a team-high total.
  • Vogelbach is 29th among all hitters in the big leagues in home runs, and 153rd in RBI.
  • Ke’Bryan Hayes has racked up a team-best batting average of .326.
  • Ben Gamel is batting .182 with a double, a home run and six walks.
Michael Chavis 8 .500 .542 .773 1 6 11
Daniel Vogelbach 10 .324 .395 .529 2 3 11
Ke’Bryan Hayes 12 .326 .356 .419 0 4 14
Ben Gamel 12 .182 .308 .303 1 5 6
Kevin Newman 9 .206 .270 .353 0 5 7

Betting Tips for Cubs vs. Pirates

Our best bet is the Pirates on the moneyline at +121 after analyzing all of the key statistics and trends for this matchup.

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