Cardinals vs. Reds Prediction, Betting Tips & Picks 4/24/2022

The Cincinnati Reds (2-13) hope to avoid their 12th straight defeat when they host the St. Louis Cardinals (9-4) Sunday at 1:40 PM ET. The Cardinals are listed as -153 favorites, while the Reds are +131 underdogs as they try to snap their losing skid. St. Louis’ Adam Wainwright gets the start, and he’ll go against Cincinnati’s Nick Lodolo.

Cardinals vs. Reds Spread and Betting Line

Computer Predictions for Cardinals vs. Reds

Our computer pick: Cincinnati Reds (+131) and Over (8.5)

Cardinals vs. Reds Game Info

• St. Louis Cardinals probable starting pitcher: Adam Wainwright
• Cincinnati Reds probable starting pitcher: Nick Lodolo
• Game Day: Sunday, April 24, 2022
• Game Time: 1:40 PM ET
• Location: Cincinnati, Ohio
• Stadium: Great American Ball Park

St. Louis Cardinals vs Cincinnati Reds Pitching Matchup

Cardinals Starter Adam Wainwright

• The Cardinals are sending Wainwright (2-1) out to make his fourth start of the season. He is 2-1 with a 2.81 ERA and 19 strikeouts through 16 innings pitched.
• The right-hander last pitched on Tuesday against the Miami Marlins, when he threw 5 2/3 innings, allowing one earned run while giving up five hits.
• The 40-year-old has an ERA of 2.81, with 10.7 strikeouts per nine innings, in three games this season. Opposing hitters have a .281 batting average against him.
• He meets a Reds offense that ranks 28th in the league with 39 runs while batting .180 as a unit. It has a collective .271 slugging percentage (30th in MLB play) and has hit a total of nine home runs (27th in MLB).
• Among qualifying pitchers in MLB play this season, the 40-year-old’s 2.81 ERA ranks 28th, 1.375 WHIP ranks 46th, and 10.7 K/9 ranks eighth.

Reds Starter Nick Lodolo

• Lodolo heads to the mound for the Reds to make his third start of the season, seeking his first win.
• The left-hander’s last appearance was on Tuesday, when he threw five innings, giving up three earned runs while allowing six hits against the San Diego Padres.
• He has pitched to an 8.00 ERA this season with 12.0 strikeouts per nine innings compared to 5.0 walks per nine across two games.
• Lodolo has made one start of five or more innings in two chances this season, and averages 4.2 frames when he pitches.
• The Cardinals rank 13th in MLB with 59 runs scored this season. They have a .242 batting average this campaign with 13 home runs (16th in the league).

Cardinals Betting Picks & Insights

• The Cardinals have entered the game as favorites six times this season and won five of those games.
• This season, St. Louis has won three of its four games when favored by at least -153 on the moneyline.
• The implied probability of a win from the Cardinals, based on the moneyline, is 60.5%.
• St. Louis and its opponents have gone over the total this season in five of their 13 opportunities.
• The Cardinals are 9-4-0 against the spread this season.

Reds Betting Picks & Insights

• The Reds have been underdogs in 12 games this season and have come away with the win two times (16.7%) in those contests.
• This season, Cincinnati has been victorious two times in 11 chances when named as an underdog of at least +131 or longer on the moneyline.
• The Reds have an implied victory probability of 43.3% according to the moneyline set by sportsbooks for this matchup.
• Cincinnati and their opponents have hit the over in seven of their 15 games with a total set by oddsmakers this season.
• In 15 games with a line this season, the Reds have a mark of 4-11-0 against the spread.

Cardinals Leaders & Batting Stats

• Nolan Arenado’s five homers and 14 RBI both lead the Cardinals, on top of his team-high .392 average.
• Arenado’s home runs rank him second in MLB, and he is fourth in RBI.
• Tommy Edman is hitting .341 with a double, a triple, three home runs and six walks.
• Edman ranks 16th in home runs and 40th in RBI on the year.
• Edman has 10 games in a row with at least one hit. During his last 10 games he is batting .343 with a double, a triple, two home runs, four walks and seven RBI.
• Paul Goldschmidt is batting .216 with three doubles and seven walks.
• Tyler O’Neill is batting .205 with a double, a home run and six walks.

Reds Leaders & Batting Stats

• Kyle Farmer has a team-best batting average of .255 and paces the Reds in runs batted in with a mark of seven.
• Among all hitters in the big leagues, Farmer’s home run total ranks 218th and his RBI tally ranks 61st.
• Tyler Naquin is hitting .250 with three doubles, a home run and four walks.
• Naquin ranks 103rd overall in home runs and 113th in RBI this year.
• Brandon Drury has two home runs, best in the lineup.
• Tommy Pham paces the Reds with two home runs.

Betting Tips for Cardinals vs. Reds

We have the Reds on the moneyline at +131 on the moneyline as our best bet in this contest after digging through all of the key stats and trends for this matchup. Our computer picks see the scoring going over the total of 8.5 runs.