Buffalo Bills vs. New England Patriots NFL Playoffs Betting Tips and Best Bets

by | Jan 11, 2022

The bookmakers think this year’s AFC Wild Card Round game between the Buffalo Bills and New England Patriots will be a relatively close one, with the Bills favored by 4.5 points. Highmark Stadium in Orchard Park, New York will host the matchup on January 15, 2022, starting at 8:15 PM ET. An over/under of 43.5 points has been set for the outing.

Bills vs. Patriots Betting Line and Game Info

  • Game Day: Saturday, January 15, 2022
  • Game Time: 8:15 PM ET
  • TV Channel: CBS
  • Location: Orchard Park, New York
  • Stadium: Highmark Stadium
Bills vs Patriots Betting Information
Favorite Spread Favorite spread odds Underdog spread odds Total Over total odds Under total odds
Bills -4.5 -110 -110 43.5 -110 -110

Bills vs. Patriots Best Bets

Prediction for Bills vs Patriots
Spread Pick Total Pick Predicted Score
Patriots (+4.5) Over (43.5) Bills 25, Patriots 20

Buffalo Bills Betting Tips

  • Buffalo has covered the spread nine times in 17 games.
  • The Bills are 6-4-2 as 4.5-point favorites or more.
  • Buffalo has played 17 games this season, and eight of them have gone over the total.
  • The Bills, on average, score 10.6 more points (28.4) than the Patriots allow (17.8).
  • In games where Buffalo scores over 17.8 points it has put together a record of 11-2.
  • The Bills have a 71.1-yard advantage in average yards gained versus yards allowed compared to the Patriots (381.9 to 310.8). The Bills average 5.8 yards per play, while the Patriots give up 5.3.
  • Buffalo’s record when it racks up over New England’s season average in yards allowed (310.8 per game): 11-4.
  • Buffalo Bills Leaders

  • Josh Allen has thrown for 4,407 yards, completing 63.3% of his passes and tossing 36 touchdowns and 15 interceptions this season. He’s also run for 763 yards (44.9 ypg) on 122 carries with six rushing touchdowns.
  • Devin Singletary has carried the ball 188 times for a team-high 870 yards on the ground and has found the end zone seven times.
  • Stefon Diggs’ team-high 1,225 yards as a receiver have come on 103 receptions (out of 164 targets) with 10 touchdowns.
  • Mario Addison has collected seven sacks to lead the team, while also recording eight TFL and 29 tackles.
  • Buffalo’s top-tackler, Tremaine Edmunds, has 108 tackles, seven TFL, and one interception this year.
  • Micah Hyde has picked off a team-leading five passes. He also has 74 tackles, four TFL, one sack, and 10 passes defended to his name.
  • Buffalo Bills Season Stats

    Stat Average (Total) Rank
    Pass yards 261.8 (4450) 10
    Rush yards 129.9 (2209) 6
    Points scored 28.4 (483) 3
    Pass yards against 179.2 (3047) 1
    Rush yards against 109.8 (1866) 14
    Points allowed 17 (289) 1

    New England Patriots Betting Tips

  • Against the spread, New England is 10-7-0 this year.
  • The Patriots are unbeaten ATS (1-0) as a 4.5-point underdog or more this year.
  • New England has seen nine of its 17 games go over the point total.
  • The Patriots have averaged 10.2 more points this season (27.2) than the Bills have allowed (17).
  • In games where New England scores more than 17 points this year, it has put together a record of 9-3.
  • The Bills’ defense has allowed 272.8 yards per game this year, 80.6 yards fewer than the 353.4-yard average from the Patriots’ offense. The Patriots pick up 5.9 yards per play and the Bills give up 4.8.
  • New England’s record this season when it accumulates more than Buffalo’s season average in yards allowed (272.8 per game): 8-7.
  • New England Patriots Leaders

  • Mac Jones has thrown for 3,801 yards on 67.6% passing while recording 22 touchdown passes with 13 interceptions this season.
  • The team’s top rusher, Damien Harris, has carried the ball 202 times for 929 yards (54.6 per game) with 15 touchdowns.
  • Jakobi Meyers has totaled 83 receptions this season and his team-high yardage total sits at 866 (50.9 yards per game). He’s been targeted 126 times and has two touchdowns.
  • Matthew Judon leads the team with 12.5 sacks, and also has 14 TFL and 60 tackles.
  • Ja’Whaun Bentley is the team’s top-tackler this year. He’s picked up 108 tackles, five TFL, and one sack.
  • J.C. Jackson has a team-leading eight interceptions to go along with 58 tackles, two TFL, and 23 passes defended.
  • New England Patriots Season Stats

    Stat Average (Total) Rank
    Pass yards 241.1 (4098) 14
    Rush yards 126.5 (2151) 8
    Points scored 27.2 (462) 6
    Pass yards against 202.2 (3437) 2
    Rush yards against 123.7 (2103) 22
    Points allowed 17.8 (303) 2

    Bills and Patriots Injuries

    Player Pos. Injury Status
    Player Pos. Injury Status

    • Sign Up for a FREE CONSULTATION

      Sign up now to have a free consultation and see how Jon Price and his team can turn sports into a lucrative investment for you!

    • This field is for validation purposes and should be left unchanged.

    The leading sports investment firm in the country